Presumptive and Definitive Drug Testing 101

Understanding the intricacies of toxicology testing and enhanced medication monitoring assuredly takes time and experience to comprehend. A simple drug test is likely more complicated than you may believe it to be. Understanding how advanced toxicology technology works to serve physicians, family practices, internal medicine, addiction specialists, and recovery centers is vital.  

With 27 combined years of experience as a board-certified anesthesiologist and pain medicine physician, Genotox Laboratories Matthew McCarty realized that a better screening assay was essential for verifying UDT sample authenticity. Leveraging the power of molecular diagnostic testing, he invented and co-developed ToxProtect, the first patent-pending DNA-authenticated urine drug test. ToxProtect helps physicians confidently resolve suspicious behavior, intervene early, and protect at-risk patients from escalating abuse. 

ToxProtect at Work: 

A one-time cheek swab collected allows for genomic cross-verification that conclusively determines if the urine scientifically matches the patient’s DNA. More than that, Tox Protect can also detect the presence of synthetic urine or any type of substitute liquid. 

Presumptive Vs. Definitive Drug Testing: 

The Toxicology department at Genotox Laboratories offers comprehensive drug testing in 34 distinct categories or classes. The test menu is divided to indicate Presumptive Testing (performed using Olympus AU 400/680 Autoanalyzer Systems) and Definitive Testing (performed using Agilent 1290 UHPLC Systems with 6460 Triple-Quadrupole Mass Spectrometers).

Presumptive Testing: This type of testing is used to identify the use or non-use of a drug or drug class. Results are reported qualitatively (Negative or Positive) and do not identify drugs/metabolites. The test menu includes: 

  • Codeine, Oxycodone, Opiate, Tapentadol, K2, Methadone, Carisoprodol, Phencyclidine (PCP), Barbiturates, Tricyclic Antidepressant (TCA), Cocaine Metabolites, 6-MonoacetylMorphine (6-MAM), Amphetamines, Cotinine, Benzodiazepines, Ethanol, Ethyl Glucuronide (EtG), Buprenorphine, THC, Fentanyl, Zolpidem, Meperidine*, Tramadol, Methamphetamine*

Definitive Testing: A definitive or confirmation test uses instrument analysis to positively identify the presence or quantity of a drug. An important aspect of definitive testing is the confirmation of metabolites. A metabolite profile tested normally falls under one of many parent drug categories. Parent drug categories range from opiates to antipsychotics to alcohol metabolites.

For more information about ToxProtect DNA-verified Urine Drug Testing (UDT) or the future of Telehealth solutions, visit:  https://genotoxlabs.com/nextgenudt/ or get in touch via info@genotoxlabs.com today.


Genotox Laboratories Verified Drug-Testing: Fighting Against Opioid Abuse

According to the National Institute on Drug Abuse, the misuse of opioids contributes to nearly 50, 000 deaths each year. This, on top of a rising strain on public health and economic systems, has only worsened the issue. The total economic burden including the costs of healthcare, lost productivity, addiction treatment, and criminal justice involvement totals over $70 billion. 

This epidemic, which more specifically involves the addiction and misuse of prescription pain relievers, heroin, and synthetic opioids like fentanyl began in the late 1990s when pharmaceutical companies reassured the medical community of their nonaddictive nature. Now, in 2021 it’s clear that these medications are in fact highly addictive and potentially harmful.

Besides careful administration and appropriate counseling, the most effective diagnostic for uncovering the misuse or abuse of opioids is urine-drug testing. Unfortunately, this naturally effective method can still be cheated and abused. 

The sheer amount of products and information on ‘how to cheat a drug test’ only further encourages the unlawful abuse and mistreatment of these medications. In most cases, fraudulently passing a drug test requires a synthetic or substitute urine that often slips through tests unscathed. 

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Luckily, at Genotox Laboratories, a team of medical professionals has developed an answer to the ongoing issue of drug-test-cheating. While watching someone pee in a cup, gathering saliva, blood, and hair samples have advantages, the real truth lies in DNA. 

Next GenUDT ToxProtect

NextGenUDT featuring ToxProtect is a DNA-verified Urine Drug Testing (UDT) definitively authenticates samples, reveals mislabeling errors, and detects urine sample substitutions. By adding a quick, one-time cheek swab to the urine collection process, a patient’s DNA can be matched to the DNA in the urine sample. 

Utilizing genomic cross-verification to definitively match a urine sample to its donor helps to accurately detect over 100 controlled substances and reveals the presence of synthetic or substitute human urine. The precise sample authenticity with 100% certainty represents the most important innovation for urine drug testing in the last decade. 

The Reality

“With 91 people dying every day from opioids we must rethink every part of the solution,” McCarty, a board-certified physician specializing in pain management and the CEO of Genotox Laboratories says, “Using urine-drug testing that eliminates the risks of sample substitution by those motivated to do so will be a strong step in the right direction.”

ToxProtect can help physicians confidently resolve suspicious behavior, intervene early, and protect at-risk patients from escalating abuse. Understanding exactly how to assess and treat the root of patients’ opioid addiction is imperative.  For more information about ToxProtect DNA-verified Urine Drug Testing (UDT) or the future of Telehealth solutions, visit https://genotoxlabs.com/nextgenudt/ or get in touch via info@genotoxlabs.com today.

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Telehealth: The Future of Healthcare in a Post-COVID-19 Era

Living in a digital age means that technology is consistently evolving to fit the needs of its users. Especially, as of late and in light of Covid-19, traditional in-person services have transitioned into remote services. Healthcare is no exception. 

Crowded hospitals and limited face-to-face access mean that providers depend more and more on innovative Telehealth solutions to serve their patients.  

So what is Telehealth? 

According to the Health Resources Services Administration, telehealth is the use of electronic information and telecommunications technologies to support long-distance clinical health care. More than that, it involves patient and professional health-related education, public health, and health administration training. 

These technologies include videoconferencing, store-and-forward imaging, streaming media, and remote testing and sample collection. 

Why is Telehealth the future of Healthcare? 

As Telehealth continues to grow, patients will discover that they can receive quality healthcare services from the comfort of their homes. Most Healthcare plans will eventually involve some form of remote assistance. Even critics and naysayers will be forced, over time, to adapt to telehealth practices. 

At Genotox Laboratories, we understand how telehealth can best serve the interests of patients, physicians, and medical professionals alike. NextGenUDT featuring ToxProtect DNA-verified Urine Drug Testing (UDT) the industry’s first no contact, at home drug testing service. On-demand test results are delivered to a clinician’s EMR or web portal. 

It’s vital that remote testing is authentic and accurate. This includes opiates and opioids, antipsychotics, skeletal muscle relaxants, stimulants, cannabinoids, and other illicit drugs.

Knowing an at-home drug test definitively authenticates samples, reveals mislabeling errors, and detects urine sample substitutions is important. Not to mention, it encourages patients down the right path towards sobriety. 

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For more information about ToxProtect DNA-verified Urine Drug Testing (UDT) or the future of Telehealth solutions, visit https://genotoxlabs.com/nextgenudt/ . Or get in touch via info@genotoxlabs.com today.


Genotox Laboratories: The Best At-Home Drug Testing Kit for Physicians

The next best alternative to an in-person witness for drug testing is Genotox Laboratories Revolutionary ToxProtect™ DNA-based urine drug test. The absence of in-person connection due to Covid-19 shouldn’t be a reason to abandon the most authentically verified methods of drug testing. 

As physicians, drug tests should be accurate and verifiable. NextGenUDT featuring ToxProtect DNA-verified Urine Drug Testing (UDT) serves the best interests of patients, physicians, and medical professionals alike. 

Knowing an at-home drug test authenticates samples, reveals mislabeling errors, and detects urine sample substitutions, encourages patients down the right path towards sobriety. Here, adding a cheek swab makes the difference in verifying an authentic sample.

While an array of convincing reasons for physicians to take advantage of this revolutionary telehealth technology exist, the following variables highlight why deciding to invest in NextGenUDT featuring ToxProtect DNA-verified Urine Drug Testing (UDT) is a no brainer: 

Benefits:

Next day results: 98% of NextGenUDT drug test results are report in under 32 hours which is shorter than average. Results should be quick and efficent, given the growing problems with drug misuse, abuse, and diversion leading to more serious issues. 

Growing painmed panel: Testing for Non-opioid monitoring is available through ToxProtect DNA-verified Urine Drug Testing (UDT). This includes testing for various opiates and opioids, antipsychotics, skeletal muscle relaxants, stimulants, cannabinoids, and other illicit drugs.

Psych complete panel: ToxProtect DNA-verified Urine Drug Testing (UDT) provides a complete clinical picture and history of a patient’s care.  

Results connect: Understanding more than a simple positive or negative result is important. Not to mention, Gentox’s integration of an easy to access physicians portal.  

Reflexive dilution: ToxProtect DNA-verified Urine Drug Testing (UDT) effectively Quantifies out-of-range values

Get in Touch:

Although UDT’s are a necessary tool for medication and sobriety monitoring, they can challenge the physician-patient relationship, especially when disagreements arise over results. Ideally, the process should unfold in a smooth, accurate, and respectful manner. For more information about ToxProtect DNA-verified Urine Drug Testing (UDT), visit https://genotoxlabs.com/nextgenudt/ or get in touch via info@genotoxlabs.com today.